A couple undergoes surgery. Derek and Meredith’s clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.

The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn’t enough to stop one woman from spending time with him. Christina is affected by…

Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek’s clinical trial experiences one or two developments.

Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the…

George has a surprise visitor. Bailey’s family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn’t inspire hope or happiness in her. Alex treats…

Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a…

There has been a bus crash and the patients are in the ER. Meredith and Derek’s relationship gets more complicated when he dates a fellow doctor. Meredith’s dad goes to…

An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava…

Izzie and George’s new-founded relationship results in them having bad sex. Callie’s Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith can barely handle…

A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them…

It’s Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers…

The doctors meet the world’s oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords…

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father…

A patient is in the hospital because they fell asleep in a hazardous situation. A patient’s home laboratory blew up in an apartment building and the victims flood the hospital….

Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced…

The interns finally take their first year medical exams, the biggest test of their careers, and one of them is ill-prepared. Callie grows more suspicious of George and Izzie. The…

The mountain climbers lie about the axe in their friend’s head, telling Derek that it accidentally got there. During surgery, he and George discover that it was deliberately put there,…

Meredith works on her relationship with Susan and Thatcher. Cristina has to deal with her mother and Burke’s. Alex continues to tend to Jane Doe/Ava. Meredith and Derek’s relationship has…

Meredith works on her relationship with Susan and Thatcher. Cristina has to deal with her mother and Burke’s. Alex continues to tend to Jane Doe/Ava. Meredith and Derek’s relationship has…

The attendings vie to be Chief. Two people who haven’t slept together before, will. McSteamy’s 60-day vow of chastity has a conclusion. We meet a boss, his assistant, and his…

Colin Marlow continues to try to get in the way of Cristina and Burke’s relationship. The daughter that Izzie gave up for adoption needs something from her. This episode features…

The race between the attending physicians for the Chief of Surgery position heats up after a new competitor enters the fray. They soon realize that the new surgeon, Colin Marlow,…

In the aftermath of Izzie’s affair with George, he doesn’t seem to remember anything. Callie lets him know that they will be having dinner with her father, but George does…

Everyone is pushing for Meredith to survive, or in this case to be revived. People are still dealing with the fallout from the ferry disaster. A young man named Lucas…

Meredith is still underwater, but nobody seems to notice. Her worsening condition makes her rescuing an urgent matter. Derek finds her coat on a man she had helped, and starts…

A mass trauma situation, which turns out to be a ferryboat accident, challenges the whole staff of Seattle Grace Hospital. Richard finds difficulty in coping with his separation from his…

After the Chief announces his retirement, rumors begin to circulate on his departure and successor. Mark is determined to leave Seattle for good but Meredith accidentally has him stay after…

The race for the Chief’s position is on, and the attending physicians, Derek, Burke, Addison and Mark, compete for Richard’s affections by trying to help out everywhere possible. The Denny…

Cristina and Burke continue to play Uncle until one of them gives in. Derek and Meredith are fighting over the reason for their sleepless nights. Meredith tries to talk to…

Meredith discovers that Derek has a problem sleeping while her father comes to visit the hospital. George’s father is moving from one surgery to another. A patient named Heather checks…

Recent events strain Burke and Cristina’s relationship. Mark and Derek must work together when two close-knit brothers seek medical help. One of Meredith’s half sisters is admitted to the hospital.

A traumatic car accident fills the ER. Izzie pushes the boundaries of her probation. Cristina has a crisis of conscience about her deceptive teamwork with Burke.

George’s father has a serious heart problem that requires surgery and George chooses Burke to do the procedure. Burke doubts himself because he knows the pressure this kind of surgery…

The men of Seattle Grace go on a camping trip together, Addison and Callie must team up to work on a patient, Meredith assists Sloan with a procedure unlike any…

Cristina gets to scrub in on a rare surgery which incites envy. Alex questions his future in plastics. George and Addison work together with Noelle. Noelle is pregnant with twins…

Derek learns one of Addison’s secrets. Bailey talks about motherhood and depression to a mother who is set to have cancer surgery and who seems to not care about any…

The staff tries to prevent a patient from getting an elective surgery. Cristina tries to help Preston cope with the after effects of his surgery. A patient bails on their…

Shawn Sullivan, a car salesman who just had surgery, wants to get back to his routine so he doesn’t lose his renown. Addison works with a pregnant woman named Rebecca…

Cristina meets Burke’s parents, the interns try to get Izzie’s job back, and Addison takes a day off, a surgical patient may be living her last day. Some of the…

Meredith must make an important choice about which path she wants to follow to determine the future of her love life. While she considers her future she and others have…