The doctors become nostalgic when George O’Malley’s mother, Louise, returns to Seattle Grace for medical help after a botched surgery at a neighboring hospital; the residents are inspired by a…

Owen stresses teamwork and moves his leadership role over to the baseball field when he signs the doctors up for a baseball league, pitting them against their biggest competition, Seattle…

After being blackballed by most of the surgeons, Meredith uses Lexie to spark Derek’s interest in her patient’s rare brain tumor case and, in secret, gives guidance to April with…

The residents try their hardest to impress surgical great Catherine Avery-who also happens to be Jackson’s mother-when she arrives at Seattle Grace to perform a groundbreaking transplant surgery; Arizona and…

The chief makes a decision that shocks everyone at Seattle Grace; Owen and Cristina attempt to find normalcy; April struggles in her new role; the 5th-year residents receive their first…

A stampede at a comic book convention leads to an influx of colorful characters in the ER; Mark continues to make life difficult for Jackson; Ben returns and realizes Bailey…

News of Meredith and Derek’s unsteady relationship raises a red flag for Zola’s adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out…

The fifth-year residents return for the first day of a year that will make or break their careers: Meredith faces the consequences of tampering with Derek’s clinical trial and is…

News of Meredith’s dishonesty in the clinical trial comes to light, leading to unanticipated consequences for her and others; Cristina finds herself in a compromising situation, which forces her to…

Personal and work pressures are adding up and have Meredith visibly on edge, Owen conducts formal interviews for the Chief Resident position, Cristina grows increasingly defiant, Alex and Lucy’s undefined…

As Callie and Arizona’s wedding approaches, the couple quickly realize that the day they’ve been looking forward to is not turning out the way they’d envisioned. Meanwhile Alex continues to…

Everyone pulls together to help Callie and baby Sofia on their painstaking journeys to recovery in hopes of allowing mother and baby to finally meet; the sudden death of a…

A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer’s trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of…

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour’s time when she steps up to run the ER for a…

Meredith must choose between her fertility treatments and her eyesight when she begins having trouble seeing, Mark makes it clear to Callie and Arizona that he takes his role as…

Thatcher Grey, Meredith and Lexie’s father, returns to Seattle Grace with stomach pains and a new, twenty-something tattooed girlfriend, Danielle. Meanwhile, Alex clashes with the new OB, Dr. Lucy Fields,…

Derek breaks ground on his Alzheimer’s clinical trial and Meredith can’t help but feel left out; Bailey’s attempt to take the hospital into the age of new media with live…

Arizona tries to reconcile with Callie, who has big news to share; Teddy faces an important decision; the residents receive new interns; the Chief makes an announcement.

A gunman opens fire at a local college, sending mass casualties to the hospital; Arizona’s return is not warmly received.

Derek takes Cristina out on a fishing trip; Teddy tries to help a patient who lacks the proper insurance to seek medical treatment.

The residents are on their own with the dreaded night shifts while the attendings go out to play to celebrate Derek’s grant for his clinical trial.

A team of doctors tries to save the life of a political figure from the Middle East; Cristina decides to decorate her new place and throw a housewarming party; Alex…

Owen puts the residents through a rigorous trauma certification drill; Cristina is left alone to monitor an ill lung transplant patient.

A documentary crew visits the hospital six months after the shooting to document the road to recovery for doctors and patients; Meredith helps Cristina put on a brave face for…

Derek and Meredith visit the obstetrician and receive disturbing news; Lexie notices April and Meredith growing closer; Jackson tries to get ahead in the operating room.

As part of their training, Seattle Grace’s residents are put in charge; the attending surgeons compete for a million-dollar grant.

Issues surface when Derek’s estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery.

Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won’t let Alex operate until he has the bullet in his chest removed.

In the wake of the shooting at Seattle Grace-Mercy West, the doctors find themselves in a frenzy: Christina and Owen will be getting married, and others are trying to deal…

Seattle Grace Hospital is hit with a crisis like no other in its’ history.

Cristina and Meredith’s surgical skills are put to the ultimate test.

An elderly patient admitted into the E.R. for a heart condition sees a familiar face, a long lost love who happens to be in the E.R. as well for a…

Bailey preps the team with mandatory sensitivity training prior to admitting a 700-pound patient with compounded medical issues, and the case proves to be challenging in every sense of the…

Sloan returns to Mark’s apartment, just as she’s going into labor, and Teddy, Mark and the still-fighting Callie and Arizona are there to help with the birth and to get…

When Alex’s younger brother, Aaron, shows up at Seattle Grace-Mercy West with a hernia, it’s up to Alex to get Bailey’s approval for his pro bono surgery. Matters are further…

A patient who needs an extremely difficult surgery comes to Seattle Grace, and it’s Richard and Owen who vie for the opportunity to tackle it. But the decision lies in…

When Teddy’s patient seeks to end treatment and her life, she turns to Hunt for help. The situation triggers Hunt’s memories of his life at war and his past relationship…

When famous surgeon Dr. Harper Avery is rushed to Seattle Grace-Mercy West, the staff is surprised to discover that one of their own is related to this legend, and his…

In his new role as Chief, Derek restores the hospital lecture series, and Richard, Bailey and Callie present to the group pivotal surgical cases from their pasts Bailey reflects on…