Elle has a shock in store for Jacob. Rash questions his future as a doctor after treating an old girlfriend.

Iain is unexpectedly reunited with his sister when he is called out to an emergency involving his mother, but his efforts to make amends for his past have unforeseen repercussions….

Jacob takes it upon himself to track down a dangerous drug dealer in Holby.

Connie’s ready to say yes to love, but there’s just one person she needs to tell first.

Connie is faced with the prospect of never seeing Grace again.

Lofty faces the consequences of his actions and has a life-changing decision to make.

As Lofty gets the hang of his new role, could a fatal error make his victory short-lived?

Lofty has to make a statement. With his friends’ support, what will he decide to say?

Connie needs to step up and prove her love for Grace, but the clock is ticking.

Ethan is back in full swing, but his world is about to be shaken.

It’s Valentine’s Day and not everyone is feeling the love.

Dixie helps a man face the truth but will she make the right decision about her own life?

The ED is pushed to the limit, but the team pull together under difficult circumstances.

Jacob teaches a hopeless man how to approach his crush, while Ethan becomes disillusioned.

Dixie steps up as the hero but is left feeling bittersweet.

It’s Christmas Eve and spirits are high, but not everyone is feeling merry.

Cal struggles with his recent discovery but discovers he’s much braver than he thinks.

Connie dismisses Jacob’s correct instincts.

A young couple have their wedding torn apart by an unsupportive father.

The harsh conditions of the season bring some people together, but others are torn apart.

Dixie is forced to ignore her gut feeling, and Cal faces every parent’s nightmare.

Alicia is pushed to her limits and proves she’s a brilliant doctor, but will it be enough?

Jacob helps a harassed teacher to accept help, but can he take his own advice?

Things get fishy when an unlikely patient comes into the ED.

Charlie helps a father and daughter deal with their grief.

Cal’s back on an even keel. Can things only get better?

Terror comes to Holby, and the innocent get caught in the crossfire.

Iain and Dixie are pushed to the limit, but their rewards are many.

There’s a new doctor in the ED as life and death hang in the balance.

Tensions rise, and gang crime threatens to spill in to the hospital corridors.

It’s a big day for Louise as an unusual romance flourishes at Holby ED.

Jacob institutes emergency protocol after gang violence takes a deadly turn.

A patient prompts Kirsty to make some life-changing decisions.

An explosion at an airport sends shock waves through the ED.

Adam purposely mismanages the treatment of a patient accused of assaulting a young girl.

Adam decides to disregard a patient’s advance directive to not be resuscitated.

The stress of Mads’ attack weighs ever heavier on her. Will the truth finally out?

Adam’s God complex continues when he has the life of a sex offender in his hands.

Adam goes to great lengths to prove his patients come first.

Linda and Tess butt heads, while Jeff is forced to face his guilt over Polly’s death.